Invention Grant
- Patent Title: Proliferative disease detection method
- Patent Title (中): 增生病检测方法
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Application No.: US12937407Application Date: 2009-04-14
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Publication No.: US08372587B2Publication Date: 2013-02-12
- Inventor: Hiroki Nagase , Yui Shinojima , Tadashi Terui
- Applicant: Hiroki Nagase , Yui Shinojima , Tadashi Terui
- Applicant Address: JP Tokyo
- Assignee: Nihon University
- Current Assignee: Nihon University
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2008-104321 20080414
- International Application: PCT/JP2009/057524 WO 20090414
- International Announcement: WO2009/128453 WO 20091022
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/02 ; C07H21/04
Abstract:
In the present invention, the methylation of the genomic DNA a Zar1 gene specifically found in proliferative disease is used as a marker. Specifically, the present invention provides a method for detecting proliferative disease, which comprises detecting the methylation of the genomic DNA of a Zar1 gene in a biological sample. There is thereby provided a method for detecting proliferative disease, using a marker having a high detection rate and a low false positive rate.
Public/Granted literature
- US20110033864A1 PROLIFERATIVE DISEASE DETECTION METHOD Public/Granted day:2011-02-10
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