Invention Grant
US08372824B2 GABA-steroid antagonists and their use for the treatment of CNS disorders
有权
GABA类固醇拮抗剂及其用于治疗CNS疾病的用途
- Patent Title: GABA-steroid antagonists and their use for the treatment of CNS disorders
- Patent Title (中): GABA类固醇拮抗剂及其用于治疗CNS疾病的用途
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Application No.: US13372389Application Date: 2012-02-13
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Publication No.: US08372824B2Publication Date: 2013-02-12
- Inventor: Torbjorn Backstrom , Per Lundgren , Ming-De Wang
- Applicant: Torbjorn Backstrom , Per Lundgren , Ming-De Wang
- Applicant Address: SE Umea
- Assignee: Umecrine AB
- Current Assignee: Umecrine AB
- Current Assignee Address: SE Umea
- Agency: Morrison & Foerster LLP
- Main IPC: A61K31/56
- IPC: A61K31/56 ; A61P25/00
Abstract:
Compounds exhibiting 3alpha-hydroxy-5alpha/beta-steroid blocking action with no or only low antagonism against the gamma-aminobutyric acid (A) receptor (GABA-A), and compounds exhibiting partial antagonism against said receptor are presented. Methods for the prevention, treatment and/or alleviation of various CNS-disorders are suggested, as well as pharmaceutical compositions for such use.
Public/Granted literature
- US20120142657A1 GABA-STEROID ANTAGONISTS AND THEIR USE FOR THE TREATMENT OF CNS DISORDERS Public/Granted day:2012-06-07
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