Invention Grant
US08372830B2 Methods for using vasopressin antagonists with anthracycline chemotherapy agents to reduce cardiotoxicity and/or improve survival
失效
使用加压素拮抗剂与蒽环类化疗药物降低心脏毒性和/或改善生存的方法
- Patent Title: Methods for using vasopressin antagonists with anthracycline chemotherapy agents to reduce cardiotoxicity and/or improve survival
- Patent Title (中): 使用加压素拮抗剂与蒽环类化疗药物降低心脏毒性和/或改善生存的方法
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Application No.: US12600145Application Date: 2008-05-12
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Publication No.: US08372830B2Publication Date: 2013-02-12
- Inventor: Yongge Liu , Junichi Kambayashi
- Applicant: Yongge Liu , Junichi Kambayashi
- Applicant Address: JP Osaka
- Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Osaka
- Agency: Sughrue Mion, PLLC
- International Application: PCT/US2008/063374 WO 20080512
- International Announcement: WO2008/144269 WO 20081127
- Main IPC: A61K31/55
- IPC: A61K31/55 ; A61K31/13

Abstract:
The present invention relates to methods of reducing cardiotoxicity and/or improving survival from treatment with anthracycline agents comprising administering a therapeutically effective amount of a composition comprising a vasopressin antagonist compound or a pharmaceutically acceptable salt thereof as an active ingredient, administered simultaneously or prior to the anthracycline administration.
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