Invention Grant
- Patent Title: Pyrazine derivatives as enac blockers
- Patent Title (中): 吡嗪衍生物作为阻断剂
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Application No.: US13232175Application Date: 2011-09-14
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Publication No.: US08372845B2Publication Date: 2013-02-12
- Inventor: Gurdip Bhalay , Lee Edwards , Catherine Howsham , Peter Hunt , Nichola Smith
- Applicant: Gurdip Bhalay , Lee Edwards , Catherine Howsham , Peter Hunt , Nichola Smith
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Joshua Roth
- Main IPC: A61K31/497
- IPC: A61K31/497
Abstract:
Compounds of Formula I: and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 have the meanings as indicated in the specification, are useful for treating diseases mediated by blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Public/Granted literature
- US20120071479A1 PYRAZINE DERIVATIVES AS ENAC BLOCKERS Public/Granted day:2012-03-22
Information query
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