Invention Grant
US08372847B2 Pyrazinone modulator of corticotropin-releasing factor receptor activity
有权
吡嗪酮调节剂促肾上腺皮质激素释放因子受体活性
- Patent Title: Pyrazinone modulator of corticotropin-releasing factor receptor activity
- Patent Title (中): 吡嗪酮调节剂促肾上腺皮质激素释放因子受体活性
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Application No.: US13052458Application Date: 2011-03-21
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Publication No.: US08372847B2Publication Date: 2013-02-12
- Inventor: Richard A. Hartz , Vijay T. Ahuja , Vivekananda M. Vrudhula , Joanne J. Bronson
- Applicant: Richard A. Hartz , Vijay T. Ahuja , Vivekananda M. Vrudhula , Joanne J. Bronson
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent James Epperson
- Main IPC: A61K31/4965
- IPC: A61K31/4965
Abstract:
The invention relates to the compound (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-(6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile, pharmaceutical compositions of the compound, and methods of using the compound for the treatment of psychiatric disorders and neurological diseases including depression, anxiety related disorders, irritable bowel syndrome, addiction and negative aspects of drug and alcohol withdrawal, and other conditions associated with CRF.
Public/Granted literature
- US20110166160A1 Pyrazinone Modulator of Corticotropin-Releasing Factor Receptor Activity Public/Granted day:2011-07-07
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