Invention Grant
US08372888B2 Sphingosine kinase type 1 inhibitors, compositions and processes for using same
有权
鞘氨醇激酶1型抑制剂，组合物及其使用方法
- Patent Title: Sphingosine kinase type 1 inhibitors, compositions and processes for using same
- Patent Title (中): 鞘氨醇激酶1型抑制剂，组合物及其使用方法
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Application No.: US12387228Application Date: 2009-04-29
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Publication No.: US08372888B2Publication Date: 2013-02-12
- Inventor: Robert E. Zipkin , Sarah Spiegel , Jeffrey Kroll Adams
- Applicant: Robert E. Zipkin , Sarah Spiegel , Jeffrey Kroll Adams
- Applicant Address: US NY Farmingdale
- Assignee: Enzo Therapeutics, Inc.
- Current Assignee: Enzo Therapeutics, Inc.
- Current Assignee Address: US NY Farmingdale
- Agent Elie Gendloff, Esq.
- Main IPC: A61K31/133
- IPC: A61K31/133
Abstract:
Provided are novel compositions which uniquely inhibit sphingosine kinase Type 1 (SphK1) and which are useful in a number of applications including killing or damaging cancer cells, inducing apoptosis, inhibiting growth, metastasis and development of chemoresistance in cancer cells, leukemia, increasing the effectiveness of anti-cancer agents, attenuating immune reactivity, inhibiting survival signaling in cancer cells, and reducing symptoms of multiple sclerosis.
Public/Granted literature
- US20100035959A1 Novel sphingosine kinase type 1 inhibitors, compositions and processes for using same Public/Granted day:2010-02-11
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