Invention Grant
- Patent Title: Phage display libraries of human VH fragments
- Patent Title (中): 噬菌体展示人VH片段的文库
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Application No.: US10451585Application Date: 2001-12-21
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Publication No.: US08372954B2Publication Date: 2013-02-12
- Inventor: Jamshid Tanha , Joycelyn Entwistle , Saran Narang , Michael Dan , Colin R. Mackenzie , Howard Kaplan
- Applicant: Jamshid Tanha , Joycelyn Entwistle , Saran Narang , Michael Dan , Colin R. Mackenzie , Carole Grad
- Applicant Address: CA Ottawa
- Assignee: National Research Council of Canada
- Current Assignee: National Research Council of Canada
- Current Assignee Address: CA Ottawa
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/CA01/01845 WO 20011221
- International Announcement: WO02/051870 WO 20020704
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C40B40/10
Abstract:
Phage display libraries are taught in which the recombinant phage population displays a plurality of potential binding fragments having preferred characteristics of solubility and/or intermolecular interaction. Also taught are methods of biasing display libraries to produce variants which more closely approximate the preferred characteristics of the parental binding fragment.
Public/Granted literature
- US20050164180A1 Phage diplay libraries of human vh fragments Public/Granted day:2005-07-28
Information query
