Invention Grant
US08372957B2 Antibody against periostin, and a pharmaceutical composition comprising it for preventing or treating a disease in which periostin is involved
有权
针对骨膜素的抗体，以及包含其用于预防或治疗涉及骨膜素的疾病的药物组合物
- Patent Title: Antibody against periostin, and a pharmaceutical composition comprising it for preventing or treating a disease in which periostin is involved
- Patent Title (中): 针对骨膜素的抗体，以及包含其用于预防或治疗涉及骨膜素的疾病的药物组合物
-
Application No.: US13198618Application Date: 2011-08-04
-
Publication No.: US08372957B2Publication Date: 2013-02-12
- Inventor: Yoshiaki Taniyama , Ryuichi Morishita , Naruto Katsuragi
- Applicant: Yoshiaki Taniyama , Ryuichi Morishita , Naruto Katsuragi
- Applicant Address: JP Tokyo JP Osaka
- Assignee: Daiichi Sankyo Company, Limited,Osaka University
- Current Assignee: Daiichi Sankyo Company, Limited,Osaka University
- Current Assignee Address: JP Tokyo JP Osaka
- Agency: Hunton & Williams LLP
- Priority: JP2005-380009 20051228; JP2007-169494 20070627; JP2008-033827 20080214
- Main IPC: C07K16/00
- IPC: C07K16/00
Abstract:
The present invention provides an antibody against a periostin isoform having anti-cell adhesive activity, especially an anti-periostin antibody having the ability to neutralize anti-cell adhesive properties, as well as a prophylactic or therapeutic agent for periostin-related diseases comprising the antibody. The present invention also provides methods for detecting and quantifying the periostin isoform in a sample by using the antibody, as well as a method for diagnosing periostin-related diseases comprising measuring the amount of the periostin isoform by the detection or quantification method.
Public/Granted literature
Information query
