- Patent Title: Compositions and methods to control angiogenesis with cupredoxins
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Application No.: US13405663Application Date: 2012-02-27
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Publication No.: US08372962B2Publication Date: 2013-02-12
- Inventor: Rajeshwari R. Mehta , Brad N. Taylor , Tohru Yamada , Craig W. Beattie , Tapas K. Das Gupta , Ananda M. Chakrabarty
- Applicant: Rajeshwari R. Mehta , Brad N. Taylor , Tohru Yamada , Craig W. Beattie , Tapas K. Das Gupta , Ananda M. Chakrabarty
- Applicant Address: US IL Urbana
- Assignee: The Board of Trustees of the University of Illinois
- Current Assignee: The Board of Trustees of the University of Illinois
- Current Assignee Address: US IL Urbana
- Agency: Sheppard, Mullin, Richter & Hampton LLP
- Agent Don J. Pelto, Esquire
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N1/20
Abstract:
The present invention relates to compositions comprising cupredoxins, and their use to inhibit angiogenesis in mammalian cells, tissues, and animals, and particularly the angiogenesis that accompanies tumor development and particularly in humans. Specifically, the present invention relates to compositions comprising the cupredoxin(s), and or peptides that are variants, derivatives or structural equivalents of cupredoxins, which retain the ability to inhibit angiogenesis in mammalian cells, tissues or animals. These compositions may be peptides or pharmaceutical compositions, among others. The compositions of the invention may be used to treat any pathological condition that has as a symptom or cause, inappropriate angiogenesis, and particularly inappropriate angiogenesis related to tumor development.
Public/Granted literature
- US20120196805A1 COMPOSITIONS AND METHODS TO CONTROL ANGIOGENESIS WITH CUPREDOXINS Public/Granted day:2012-08-02
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