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US08373114B2 Total carbon mass determination by accelerator mass spectrometry (AMS) using 13C isotope dilution 失效
通过使用13C同位素稀释的加速器质谱法(AMS)测定总碳质量

  • Patent Title: Total carbon mass determination by accelerator mass spectrometry (AMS) using 13C isotope dilution
  • Patent Title (中): 通过使用13C同位素稀释的加速器质谱法(AMS)测定总碳质量
  • Application No.: US12559470
    Application Date: 2009-09-14
  • Publication No.: US08373114B2
    Publication Date: 2013-02-12
  • Inventor: Ali ArjomandUgo ZoppiJames Crye
  • Applicant: Ali ArjomandUgo ZoppiJames Crye
  • Applicant Address: US WA Seattle
  • Assignee: Accium Biosciences
  • Current Assignee: Accium Biosciences
  • Current Assignee Address: US WA Seattle
  • Agent Jeffrey B. Oster
  • Main IPC: B01D59/44
  • IPC: B01D59/44
Total carbon mass determination by accelerator mass spectrometry (AMS) using 13C isotope dilution
Abstract:
There is disclosed a method for direct quantitation of total carbon and 14C/12C ratios in a single measurement using Accelerator Mass Spectrometry (AMS). More specifically, measurement of both total carbon and 14C/12C ratio is performed in the same sample at the same time. The disclosed method provides improved sensitivity and accuracy for reliably calculating 14C-labeled compound concentrations in biological samples. There is also a reduction in measurement time, sample volume requirement and measurement cost compared to existing procedures.
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