A method for assisting diagnosis of stroke by image analysis, the method comprising obtaining a scanned brain image of a patient, transforming the scanned brain image into a digitized brain image, removing bone and other artifacts from the digitized brain image, generating at least one circular adaptive region of interest on one side of the brain image, generating a binary mask of the circular adaptive region of interest, calculating the percentage of zeros from the binary mask within the circular adaptive region of interest, locating at least one corresponding circular adaptive region of interest on the other side of the brain image, and comparing the circular adaptive region of interest with the corresponding circular adaptive region on interest of the other side of the brain based on a plurality of texture attributes.