A system and method for telemetrically collecting on-road vehicle diagnostic data. In one embodiment, the method includes collecting vehicle diagnostic data from service shops, on-road vehicles and warranty records, aggregating the collected data and extracting knowledge therefrom. The extracted knowledge can be used to enhance algorithms on-board vehicles or at service centers so as to better identify vehicle faults and provide enhanced diagnostics and prognostics. The enhanced algorithms can then be used to provide predictive maintenance suggestions, provide trouble shooting assistance or provide vehicle design improvements.