A ball valve with single access port includes a ball valve body; a ball disposed inside the ball valve body, the ball having an open inside portion creating a primary passage, an operating position of the ball determining the flow of fluid and pressurized cleaning agent through the valve; a secondary passage configured to allow the flow of the pressurized cleaning agent into the open inside portion of the ball and an access port allowing an external source of the pressurized cleaning agent to be coupled to the ball valve.