Invention Grant
- Patent Title: Bacteriophage or lytic protein derived from the bacteriophage which effective for the treatment of Staphylococcus aureus biofilm
- Patent Title (中): 来源于有效治疗金黄色葡萄球菌生物膜的噬菌体的噬菌体或裂解蛋白
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Application No.: US12677990Application Date: 2008-09-12
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Publication No.: US08377431B2Publication Date: 2013-02-19
- Inventor: Seongjun Yoon , Yunjaie Choi , Se Yung Lee , Jeesoo Son , Sooyoun Jun , Sanghyeon Kang
- Applicant: Seongjun Yoon , Yunjaie Choi , Se Yung Lee , Jeesoo Son , Sooyoun Jun , Sanghyeon Kang
- Applicant Address: KR Sungnam-Si
- Assignee: iNtRON Biotechnology, Inc.
- Current Assignee: iNtRON Biotechnology, Inc.
- Current Assignee Address: KR Sungnam-Si
- Agency: Ballard Spahr LLP
- Priority: KR10-2007-0092859 20070913
- International Application: PCT/KR2008/005434 WO 20080912
- International Announcement: WO2009/035303 WO 20090319
- Main IPC: A01N63/00
- IPC: A01N63/00

Abstract:
The present invention relates to compositions for removing a biofilm formed by Staphylococcus aureus, comprising a bacteriophage, such as Myoviridae family T4-like phage genus bacteriophage (Accession No: KCTC 11153BP, SAP-1) or Podoviridae family φ29-like virus genus bacteriophage (Accession No: KCTC11154BP, SAP-2), and lytic protein derived therefrom, that destroys the biofilm. Also disclosed are pharmaceutical compositions for the treatment of diseases caused by Staphylococcus aureus capable of forming biofilm.
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