Invention Grant
- Patent Title: Methods of antagonizing signal transduction in spinal cord cells
- Patent Title (中): 拮抗脊髓细胞信号转导的方法
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Application No.: US13331145Application Date: 2011-12-20
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Publication No.: US08377438B2Publication Date: 2013-02-19
- Inventor: Yue Yao , Janine Bilsborough
- Applicant: Yue Yao , Janine Bilsborough
- Applicant Address: US WA Seattle
- Assignee: ZymoGenetics, Inc.
- Current Assignee: ZymoGenetics, Inc.
- Current Assignee Address: US WA Seattle
- Agent Brian J. Walsh; Robyn Adams
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K38/00 ; C07K16/28 ; C07K14/435 ; C07K14/00
Abstract:
Use of antagonists to IL-31 are used to treat inflammation and pain by inhibiting, preventing, reducing, minimizing, limiting or minimizing stimulation in neuronal tissues. Such antagonists include antibodies and fragments, derivative, or variants thereof. Symptoms such as pain, tingle, sensitization, tickle associated with neuropathies are ameliorated.
Public/Granted literature
- US20120107310A1 METHODS OF ANTAGONIZING SIGNAL TRANSDUCTION IN SPINAL CORD CELLS Public/Granted day:2012-05-03
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