Invention Grant
US08377451B2 Polysaccharide-staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections
有权
多糖 - 葡萄球菌表面粘附素载体蛋白结合物免疫接种医院感染
- Patent Title: Polysaccharide-staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections
- Patent Title (中): 多糖 - 葡萄球菌表面粘附素载体蛋白结合物免疫接种医院感染
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Application No.: US11593481Application Date: 2006-11-07
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Publication No.: US08377451B2Publication Date: 2013-02-19
- Inventor: Viliam Pavliak , Steven Morris Baker , Subramonia Padmanaba Pillai , Joseph M. Patti , Bradley D. Prater
- Applicant: Viliam Pavliak , Steven Morris Baker , Subramonia Padmanaba Pillai , Joseph M. Patti , Bradley D. Prater
- Applicant Address: US NJ Madison
- Assignee: Wyeth Holdings Corporation
- Current Assignee: Wyeth Holdings Corporation
- Current Assignee Address: US NJ Madison
- Agency: Stites & Harbison PLLC
- Agent B. Aaron Schulman, Esq.
- Main IPC: A61K39/02
- IPC: A61K39/02
Abstract:
Immunogenic polysaccharide-protein conjugates having a polysaccharide antigen (or its oligosaccharide fragment representing one or more antigenic epitopes) derived from a nosocomial pathogen conjugated to a staphylococcal surface adhesin carrier protein are used in immunogenic compositions to elicit antibody responses to both the polysaccharide antigen and the staphylococcal surface adhesin carrier protein. Such immunogenic compositions are used to immunize against diseases caused by Staphylococcal aureus, Staphylococcal epidermidis or other nosocomial pathogens.
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