Invention Grant
- Patent Title: Method of predicting the clinical response to cisplatin or carboplatin chemotherapeutic treatment
- Patent Title (中): 预测顺铂或卡铂化疗治疗临床反应的方法
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Application No.: US11908796Application Date: 2006-03-16
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Publication No.: US08377888B2Publication Date: 2013-02-19
- Inventor: Rafael Rosell Costa , Miguel Taron Roca
- Applicant: Rafael Rosell Costa , Miguel Taron Roca
- Applicant Address: ES Barcelona
- Assignee: Pangaea Biotech, S.A.
- Current Assignee: Pangaea Biotech, S.A.
- Current Assignee Address: ES Barcelona
- Agency: Hultquist, PLLC
- Agent Kelly K. Reynolds; Steven J. Hultquist
- Priority: EP05075632 20050316
- International Application: PCT/EP2006/002610 WO 20060316
- International Announcement: WO2006/097346 WO 20060921
- Main IPC: A61P35/00
- IPC: A61P35/00 ; C12Q1/68
Abstract:
Method for predicting the survival of a patient suffering from NSCLC to a cisplatin or carboplatin based chemotherapy treatment which comprises the step of determining the methylation state of a nucleic acid encoding 14-3-3 sigma in a biological sample from the patient, wherein the presence of methylation is indicative of longer survival of said patient as a response to said chemotherapy treatment. The methylation status of the 14-3-3 sigma gene can be easily determined in a serum sample.
Public/Granted literature
- US20090068657A1 METHOD OF PREDICTING THE CLINICAL RESPONSE TO CISPLATIN OR CARBOPLATIN CHEMOTHERAPEUTIC TREATMENT Public/Granted day:2009-03-12
Information query
IPC分类:
| A | 人类生活必需 |
| A61 | 医学或兽医学；卫生学 |
| A61P | 化合物或药物制剂的特定治疗活性 |
| A61P35/00 | 抗肿瘤药 |
