Invention Grant
- Patent Title: Polymeric prodrug with a self-immolative linker
- Patent Title (中): 具有自褪色接头的聚合前药
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Application No.: US10594097Application Date: 2005-03-22
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Publication No.: US08377917B2Publication Date: 2013-02-19
- Inventor: Ulrich Hersel , Harald Rau , Robert Schnepf , Dirk Vetter , Thomas Wegge
- Applicant: Ulrich Hersel , Harald Rau , Robert Schnepf , Dirk Vetter , Thomas Wegge
- Applicant Address: DE Heidelberg
- Assignee: Complex BioSystems GmbH
- Current Assignee: Complex BioSystems GmbH
- Current Assignee Address: DE Heidelberg
- Agency: Novak Druce Connolly Bove + Quigg LLP
- Priority: EP04075892 20040323; GB0415043.9 20040705; EP04019293 20040813
- International Application: PCT/EP2005/003061 WO 20050322
- International Announcement: WO2005/099768 WO 20051027
- Main IPC: A61K31/33
- IPC: A61K31/33

Abstract:
A cascade carrier linked prodrug is described which comprises a biologically active moiety and a masking group having at least one nucleophile and being distinct from the carrier.
Public/Granted literature
- US20080241102A1 Polymeric Prodrug with a Self-Immolative Linker Public/Granted day:2008-10-02
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