Invention Grant
- Patent Title: Phenoxypyridine derivative salts and crystals thereof, and process for preparing the same
- Patent Title (中): 苯氧基吡啶衍生物盐及其晶体及其制备方法
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Application No.: US12031568Application Date: 2008-02-14
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Publication No.: US08377938B2Publication Date: 2013-02-19
- Inventor: Tomohiro Matsushima , Shuji Shirotori , Keiko Takahashi , Atsushi Kamada , Kazunori Wakasugi , Takahisa Sakaguchi
- Applicant: Tomohiro Matsushima , Shuji Shirotori , Keiko Takahashi , Atsushi Kamada , Kazunori Wakasugi , Takahisa Sakaguchi
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JPP2007-036690 20070216
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/4427 ; C07D401/12
Abstract:
The invention provides acid addition salts of the compounds represented by formula (1) or (2), or crystals thereof, and processes for preparing the same. The salts or crystals have HGFR inhibitory activity and excellent physical properties (solubility, safety, etc.) and are therefore useful as anti-tumor agents, angiogenesis inhibitors and inhibitors for metastasis for a various types of tumor.
Public/Granted literature
- US20080318924A1 PHENOXYPYRIDINE DERIVATIVE SALTS AND CRYSTALS THEREOF, AND PROCESS FOR PREPARING THE SAME Public/Granted day:2008-12-25
Information query
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