Invention Grant
US08377941B2 Indoles as modulators of nicotinic acetylcholine receptor subtype alpha-7
失效
吲哚作为烟碱型乙酰胆碱受体亚型α-7的调节剂
- Patent Title: Indoles as modulators of nicotinic acetylcholine receptor subtype alpha-7
- Patent Title (中): 吲哚作为烟碱型乙酰胆碱受体亚型α-7的调节剂
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Application No.: US12936431Application Date: 2009-04-16
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Publication No.: US08377941B2Publication Date: 2013-02-19
- Inventor: Kevin Dinnell , Andrew P Lightfoot , Howard Robert Marshall
- Applicant: Kevin Dinnell , Andrew P Lightfoot , Howard Robert Marshall
- Applicant Address: GB London
- Assignee: Proximagen Limited
- Current Assignee: Proximagen Limited
- Current Assignee Address: GB London
- Agency: Banner & Witcoff, Ltd.
- Priority: GB0807050.0 20080417; GB0810229.5 20080604
- International Application: PCT/EP2009/054495 WO 20090416
- International Announcement: WO2009/127679 WO 20091022
- Main IPC: C07D239/28
- IPC: C07D239/28 ; A61K31/166 ; A61K31/404 ; A61K31/505
Abstract:
The present invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of List A or a salt thereof, which may be represented, but is not limited to the compound N-[(2-Trifluoromethyl-1H-indol-5-yl)methyl]-2-(trifluoromethyl)-5-pyrimidinecarboxamide.
Public/Granted literature
- US20110028486A1 INDOLES AS MODULATORS OF NICOTICIC ACETYLCHOLINE RECEPTOR SUBTYPE ALPHA-7 Public/Granted day:2011-02-03
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