Invention Grant
US08377955B2 Branched 3- and 6-substituted quinolines as CGRP receptors antagonists
有权
分支的3-和6-取代的喹啉作为CGRP受体拮抗剂
- Patent Title: Branched 3- and 6-substituted quinolines as CGRP receptors antagonists
- Patent Title (中): 分支的3-和6-取代的喹啉作为CGRP受体拮抗剂
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Application No.: US12997033Application Date: 2009-06-03
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Publication No.: US08377955B2Publication Date: 2013-02-19
- Inventor: Michael R. Wood , June J. Kim , Kathy Schirripa
- Applicant: Michael R. Wood , June J. Kim , Kathy Schirripa
- Applicant Address: US NJ Rahway
- Assignee: Merck, Sharp & Dohme, Corp.
- Current Assignee: Merck, Sharp & Dohme, Corp.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; Gerard M. Devlin
- International Application: PCT/US2009/046107 WO 20090603
- International Announcement: WO2009/152010 WO 20091217
- Main IPC: A61K31/473
- IPC: A61K31/473 ; C07D471/20
Abstract:
The present invention is directed to novel branched 3- and 6-substituted quinoline derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Public/Granted literature
- US20110105549A1 BRANCHED 3- AND 6-SUBSTITUTED QUINOLINES AS CGRP RECEPTORS ANTAGONISTS Public/Granted day:2011-05-05
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