A random number generator includes a first one time programmable (OTP) element and a second OTP element. The first OTP element and second OTP element have a first distribution of probable values for an electrical characteristic when unprogrammed and a second distribution of probable values when programmed. A programming circuit applies a programming signal to the first OTP element and to the second OTP element that causes the first OTP element to switch from being unprogrammed to being programmed and having a first value for its electrical characteristic and the second OTP element to switch from being unprogrammed to being programmed and having a second value for its electrical characteristic. A sense amplifier provides an output signal at a first logic state when the first value exceeds the second value and at a second logic state when the second value exceeds the first value.