A system includes a master device and multiple slave devices. The system also includes multiple bus interfaces forming a communication bus that couples the master and slave devices. Each bus interface includes a primary interface unit configured to communicate over first and second buses, where the first and second buses form a portion of the communication bus. Each bus interface also includes a secondary interface unit configured to communicate with the primary interface unit and to communicate with one of the slave devices over a third bus. Each bus interface further includes an isolator configured to electrically isolate the primary interface unit and the secondary interface unit. The primary interface unit is configured to receive multiple commands over the first bus, execute a first subset of commands, transmit a second subset of commands over the second bus, and transmit a third subset of commands over the third bus.