Embodiments of systems, apparatuses, and methods for emulating an input/output Advanced Programmable Interrupt Controller are disclosed. In one embodiment, an apparatus includes a first interrupt controller having a first programming model, and emulation logic to emulate a second interrupt controller having a second programming model that is different from the first programming model. The emulation logic is also to mask one of a plurality of interrupt requests to the first interrupt controller for each of the plurality of interrupt requests handled by the emulation logic.