A device and related method for mixing a powdered component and a liquid component with minimal user interaction are described. A powdered component and a liquid component are separately fed into a mixing chamber. The powdered component may be released into the liquid component by removing a barrier. Alternatively, the two components are drawn into the mixing chamber from respective sources by a vacuum. The mixture is sonicated at precise vibrational frequencies to control the physical properties of the final blended content. A piston-like device is used to remove the blended content from the mixing chamber.