Invention Grant
US08383120B2 Concomitant treatment of rheumatoid arthritis with anti-TNF-alpha antibodies and methotrexate
失效
用抗TNF-α抗体和甲氨蝶呤同时治疗类风湿关节炎
- Patent Title: Concomitant treatment of rheumatoid arthritis with anti-TNF-alpha antibodies and methotrexate
- Patent Title (中): 用抗TNF-α抗体和甲氨蝶呤同时治疗类风湿关节炎
-
Application No.: US13350065Application Date: 2012-01-13
-
Publication No.: US08383120B2Publication Date: 2013-02-26
- Inventor: Marc Feldmann , Ravinder N. Maini
- Applicant: Marc Feldmann , Ravinder N. Maini
- Applicant Address: GB London
- Assignee: The Mathilda and Terence Kennedy Institute of Rheumatology Trust
- Current Assignee: The Mathilda and Terence Kennedy Institute of Rheumatology Trust
- Current Assignee Address: GB London
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; A01N43/58
Abstract:
Methods for treating and/or preventing a TNF-mediated disease in an individual are disclosed. Also disclosed is a composition comprising methotrexate and an anti-tumor necrosis factor antibody. TNF-mediated diseases include rheumatoid arthritis, Crohn's disease, and acute and chronic immune diseases associated with transplantation.
Public/Granted literature
- US20120141474A1 TNF-alpha Antagonists and Methotrexate in the Treatment of TNF-Mediated Disease Public/Granted day:2012-06-07
Information query
