Invention Grant
- Patent Title: Monoclonal antibodies specific to hemagglutinin and neuraminidase from influenza virus H5-subtype or N1-subtype and uses thereof
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Application No.: US12677971Application Date: 2008-09-12
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Publication No.: US08383121B2Publication Date: 2013-02-26
- Inventor: Hong Liang Qian , Fang He , Hwei-Sing Kwang
- Applicant: Hong Liang Qian , Fang He , Hwei-Sing Kwang
- Applicant Address: SG Singapore
- Assignee: Temasek Life Sciences Laboratory Limited
- Current Assignee: Temasek Life Sciences Laboratory Limited
- Current Assignee Address: SG Singapore
- Agency: Rothwell, Figg, Ernst & Manbeck P.C.
- International Application: PCT/SG2008/000347 WO 20080912
- International Announcement: WO2009/035420 WO 20090319
- Main IPC: A61K39/42
- IPC: A61K39/42 ; C07K16/10 ; C07K17/00 ; C12Q1/70
Abstract:
Monoclonal antibodies and related binding proteins that bind specifically to the envelope glycoprotein of H5 subtypes or neuraminidase glycoprotein of N1 subtypes of avian influenza virus (AIV) are provided. The monoclonal antibodies and related binding proteins are useful for the detection of H5 and N1 subtypes of AIV, including H5N1 subtypes and provide means for the diagnosis, surveillance and treatment of dangerous viral infections.
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