Invention Grant
US08383146B2 Compositions for oral adminstration of active principles requiring masking of taste 有权
用于口服施用需要掩盖味道的活性成分的组合物

  • Patent Title: Compositions for oral adminstration of active principles requiring masking of taste
  • Patent Title (中): 用于口服施用需要掩盖味道的活性成分的组合物
  • Application No.: US13360151
    Application Date: 2012-01-27
  • Publication No.: US08383146B2
    Publication Date: 2013-02-26
  • Inventor: Isabelle ChacornacPatricia Probeck
  • Applicant: Isabelle ChacornacPatricia Probeck
  • Applicant Address: FR Paris
  • Assignee: Sanofi
  • Current Assignee: Sanofi
  • Current Assignee Address: FR Paris
  • Agent Ronald G. Ort
  • Priority: FR0216521 20021223
  • Main IPC: A61K9/14
  • IPC: A61K9/14 A61K9/28
Compositions for oral adminstration of active principles requiring masking of taste
Abstract:
A process for the preparation of a composition intended for the oral administration of active principles with unacceptable taste, which comprises from about 15% to about 30% of organoleptically unpleasant active ingredient (principle) that is mixed with from about 60% to about 80% of an ester of glycerol or of a fatty acid, to which a wax is optionally added and to which a surfactant is added, and in that it is prepared by a spray-cooling process which can produce a particle size of less than 350 μm.
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