Invention Grant
- Patent Title: HBV precore protein capable of forming particles
- Patent Title (中): HBV前蛋白能够形成颗粒
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Application No.: US12654280Application Date: 2009-12-16
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Publication No.: US08383333B2Publication Date: 2013-02-26
- Inventor: Noboru Maki , Tatsuji Kimura , Shintaro Yagi
- Applicant: Noboru Maki , Tatsuji Kimura , Shintaro Yagi
- Applicant Address: JP Saitama
- Assignee: Advanced Life Science Institute, Inc.
- Current Assignee: Advanced Life Science Institute, Inc.
- Current Assignee Address: JP Saitama
- Agency: Foley & Lardner LLP
- Priority: JP2002-261666 20020906
- Main IPC: C12Q1/70
- IPC: C12Q1/70 ; G01N33/53
Abstract:
There is provided a HBV precore protein having an ability of forming particles, and a means for determining it. A novel HBV precore protein that forms the virus (like) particles of HBV was identified. The present invention provides this novel HBV precore protein. Furthermore, there are provided core-like particles and virus-like particles formed by this HBV precore protein. These virus-like particles can be used for vaccines and therapeutic agents. The present invention also provides a method of determining the HBV precore protein and a method of determining the anti-HBV precore protein antibody.
Public/Granted literature
- US20100285444A1 HBV precore protein capable of forming particles Public/Granted day:2010-11-11
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