Invention Grant
- Patent Title: Combined automated parallel synthesis of polynucleotide variants
- Patent Title (中): 组合自动并行合成多核苷酸变体
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Application No.: US12562988Application Date: 2009-09-18
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Publication No.: US08383346B2Publication Date: 2013-02-26
- Inventor: Jeffrey Colbeck , Benjamin Mijts , Lorraine Joan Giver , Richard J. Fox , Vesna Mitchell , Bumshik Robert Pak , Lynne Gilson
- Applicant: Jeffrey Colbeck , Benjamin Mijts , Lorraine Joan Giver , Richard J. Fox , Vesna Mitchell , Bumshik Robert Pak , Lynne Gilson
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Codexis, Inc.
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/04
Abstract:
The present disclosure relates to methods for efficient synthesis, cloning, transformation and screening of large diverse libraries of polynucleotide variants comprising well-defined nucleotide differences relative to a reference polynucleotide.
Public/Granted literature
- US20100093560A1 COMBINED AUTOMATED PARALLEL SYNTHESIS OF POLYNUCLEOTIDE VARIANTS Public/Granted day:2010-04-15
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