Invention Grant
US08383371B2 Nucleic acid construct containing a nucleic acid derived from the genome of hepatitis C virus (HCV) of genotype 2a, and a cell having such nucleic acid construct introduced therein
有权
含有源自基因型2a的丙型肝炎病毒（HCV）的基因组的核酸的核酸构建体和在其中引入了这种核酸构建体的细胞
- Patent Title: Nucleic acid construct containing a nucleic acid derived from the genome of hepatitis C virus (HCV) of genotype 2a, and a cell having such nucleic acid construct introduced therein
- Patent Title (中): 含有源自基因型2a的丙型肝炎病毒（HCV）的基因组的核酸的核酸构建体和在其中引入了这种核酸构建体的细胞
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Application No.: US12958318Application Date: 2010-12-01
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Publication No.: US08383371B2Publication Date: 2013-02-26
- Inventor: Takaji Wakita , Takanobu Kato , Tomoko Date
- Applicant: Takaji Wakita , Takanobu Kato , Tomoko Date
- Applicant Address: JP Tokyo JP Tokyo DE Schriesheim
- Assignee: Toray Industries, Inc.,Tokyo Metropolitan Institute of Medical Science,Ralf Bartenschlager
- Current Assignee: Toray Industries, Inc.,Tokyo Metropolitan Institute of Medical Science,Ralf Bartenschlager
- Current Assignee Address: JP Tokyo JP Tokyo DE Schriesheim
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2003-148242 20030526; JP2003-329115 20030919
- Main IPC: C12P19/34
- IPC: C12P19/34 ; A61K31/00 ; A61K39/42 ; G01N33/53
Abstract:
The present invention relates to a replicon RNA comprising a nucleotide sequence at least containing the 5′ untranslated region, the nucleotide sequence encoding NS3 protein, NS4A protein, NS4B protein, NS5A protein and NS5B protein, and the 3′ untranslated region on the genomic RNA of hepatitis C virus of genotype 2a.
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