Invention Grant
US08383375B2 Thermostable gluconate dehydratase and use thereof 有权
高温葡萄糖酸脱水酶及其用途

Thermostable gluconate dehydratase and use thereof
Abstract:
The present invention relates to a novel thermostable gluconate dehydratase from the thermoacidophilic archaeon Sulfolobus solfataricus, a coding sequence, and an expression system. The gluconate dehydratase has a molecular weight of about 320,000 to 380,000 daltons as the native protein, and about 40,000 to 50,000 daltons as the monomer protein, and catalyzes the dehydration reaction of aldonic acids to 2-keto-3-deoxy derivatives at temperatures of less than 120° C. The gluconate dehydratase can be produced from native or recombinant host cells and thereby used in the pharmaceutical, agricultural, and other industries.
Public/Granted literature
Information query
Patent Agency Ranking
0/0