Invention Grant
- Patent Title: Thermostable gluconate dehydratase and use thereof
- Patent Title (中): 高温葡萄糖酸脱水酶及其用途
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Application No.: US12910768Application Date: 2010-10-22
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Publication No.: US08383375B2Publication Date: 2013-02-26
- Inventor: Seonghun Kim , Sun Bok Lee
- Applicant: Seonghun Kim , Sun Bok Lee
- Applicant Address: KR Nam-gu, Kyungsangbuk-do, Pohang KR Hyoja-dong, Nam-gu, Kyungsangbuk-do, Pohang
- Assignee: Posco,Postech Foundation
- Current Assignee: Posco,Postech Foundation
- Current Assignee Address: KR Nam-gu, Kyungsangbuk-do, Pohang KR Hyoja-dong, Nam-gu, Kyungsangbuk-do, Pohang
- Agency: JHK Law
- Agent Joseph Hyosuk Kim
- Main IPC: C12P7/58
- IPC: C12P7/58 ; C12P7/42 ; C12P7/50

Abstract:
The present invention relates to a novel thermostable gluconate dehydratase from the thermoacidophilic archaeon Sulfolobus solfataricus, a coding sequence, and an expression system. The gluconate dehydratase has a molecular weight of about 320,000 to 380,000 daltons as the native protein, and about 40,000 to 50,000 daltons as the monomer protein, and catalyzes the dehydration reaction of aldonic acids to 2-keto-3-deoxy derivatives at temperatures of less than 120° C. The gluconate dehydratase can be produced from native or recombinant host cells and thereby used in the pharmaceutical, agricultural, and other industries.
Public/Granted literature
- US20110111471A1 NOVEN THERMOSTABLE GLUCONATE DEHYDRATASE AND USE THEREOF Public/Granted day:2011-05-12
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