Invention Grant
- Patent Title: Bendamustine anionic-catioinic cyclopolysaccharide compositions
- Patent Title (中): 苯达莫司汀阴离子型阴离子多环多糖组合物
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Application No.: US13032168Application Date: 2011-02-22
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Publication No.: US08383663B2Publication Date: 2013-02-26
- Inventor: Valery Alakhov , Grzegorz Pietrzynski , Patel Kishore , Thomasz Popek
- Applicant: Valery Alakhov , Grzegorz Pietrzynski , Patel Kishore , Thomasz Popek
- Applicant Address: CA Montreal
- Assignee: Supratek Pharma Inc.
- Current Assignee: Supratek Pharma Inc.
- Current Assignee Address: CA Montreal
- Agency: Porzio, Bromberg & Newman, P.C.
- Main IPC: A61K31/415
- IPC: A61K31/415

Abstract:
The present invention is directed to pharmaceutical compositions including: (a) bendamustine, (b) a first charged cyclopolysaccharide, and (c) a stabilizing agent which is a second charged cyclopolysaccharide having a charge opposite to that of the first charged cyclopolysaccharide. The composition provides unexpectedly desirable stability in reactive environments such as plasma, coupled with unexpectedly desirable anticancer activity. The compositions are suitable for injection or infusion into patients in need for treatment with bendamustine.
Public/Granted literature
- US20120015995A1 BENDAMUSTINE ANIONIC-CATIOINIC CYCLOPOLYSACCHARIDE COMPOSITIONS Public/Granted day:2012-01-19
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