A method of interference suppression in a wireless cellular network includes notifying a first base station that there is a second User Equipment (UE) that currently suffers downlink interferences from the first base station, when an second UE in an active state suffers the downlink interferences from the first base station; and reallocating, by the first base station, spectrum resources for a first UE communicating with the first base station. A first base station, a second UE and a second base station for implementing the above method of interference suppression are also provided. When the second UE in the active state suffers the downlink interferences from an adjacent first base station, the first base station can adjust the spectrum resources occupied by the first UE through resource scheduling, so as to reduce the downlink interferences on the second UE in the active state, thus to reduce the influence on the communication between the second UE and the second base station.