Invention Grant
US08388964B2 Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells 有权
治疗由皮肤淋巴细胞抗原阳性细胞介导的疾病的方法

Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells
Abstract:
The present invention relates to methods of treating patients suffering from itching and puritis mediated by cutaneous lymphocyte antigen positive T cell. In particular, diseases or disorders including contact dermatitis, drug induced delayed type cutaneous allergic reactions, toxic epidermal necrolysis, cutaneous T cell lymphoma, bullous pemphigoid, alopecia aereata, vitiligo, acne rosacea, prurigo nodularis, and herpes simplex virus, or combination thereof will benefit from the administration of an IL-31 antagonist. The invention also includes methods of predicting a therapeutically responsive patient population.
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