Invention Grant
US08389266B2 Lactic acid bacterium having effect of lowering blood uric acid level
有权
具有降低血液尿酸水平的作用的乳酸菌
- Patent Title: Lactic acid bacterium having effect of lowering blood uric acid level
- Patent Title (中): 具有降低血液尿酸水平的作用的乳酸菌
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Application No.: US12745006Application Date: 2008-11-27
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Publication No.: US08389266B2Publication Date: 2013-03-05
- Inventor: Hiroshi Tsuboi , Noriko Kaneko , Akina Satou , Akinori Kume , Katsunori Kimura
- Applicant: Hiroshi Tsuboi , Noriko Kaneko , Akina Satou , Akinori Kume , Katsunori Kimura
- Applicant Address: JP Tokyo
- Assignee: Meiji Co., Ltd.
- Current Assignee: Meiji Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Cooley LLP
- Priority: JP2007-310892 20071130
- International Application: PCT/JP2008/071559 WO 20081127
- International Announcement: WO2009/069704 WO 20090604
- Main IPC: C12N1/20
- IPC: C12N1/20

Abstract:
The present invention provides lactic acid bacteria which are suitable for use for dietary products and pharmaceuticals, and which can suppress the increase of blood uric acid level. Various types of lactic acid bacteria were cultured in the presence of a purine, the amount of the purine consumed and the amount of purine degradation products produced were measured, and several lactic acid bacteria showing remarkable purine-decomposing ability were selected. Lactic acid bacteria that were assessed to have high purine-decomposing ability according to the above-mentioned selection were orally administered to rats reared on purine-containing feed, the general status and serum uric acid level of the rats were measured, and the effect of lactic acid bacteria administration on serum uric acid levels was examined. As a result, lactic acid bacteria that significantly suppress the increase of serum uric acid levels, Lactobacillus gasseri OLL2922, were found.
Public/Granted literature
- US20100316618A1 LACTIC ACID BACTERIUM HAVING EFFECT OF LOWERING BLOOD URIC ACID LEVEL Public/Granted day:2010-12-16
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