Invention Grant
- Patent Title: Bicyclic heterocyclic derivative
- Patent Title (中): 双环杂环衍生物
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Application No.: US12809489Application Date: 2008-12-19
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Publication No.: US08389511B2Publication Date: 2013-03-05
- Inventor: Hiroyuki Nakahira , Yohei Ikuma , Nobuhisa Fukuda , Kozo Yoshida , Hidenori Kimura , Satoshi Suetsugu , Akira Fusano , Kiyoto Sawamura , Junya Ikeda , Yoshio Nakai
- Applicant: Hiroyuki Nakahira , Yohei Ikuma , Nobuhisa Fukuda , Kozo Yoshida , Hidenori Kimura , Satoshi Suetsugu , Akira Fusano , Kiyoto Sawamura , Junya Ikeda , Yoshio Nakai
- Applicant Address: JP Osaka
- Assignee: Dainippon Sumitomo Pharma Co., Ltd.
- Current Assignee: Dainippon Sumitomo Pharma Co., Ltd.
- Current Assignee Address: JP Osaka
- Agency: Sughrue Mion, PLLC
- Priority: JP2007-328087 20071219; JP2008-202960 20080806
- International Application: PCT/JP2008/073184 WO 20081219
- International Announcement: WO2009/078481 WO 20090625
- Main IPC: A61K31/5415
- IPC: A61K31/5415 ; A61K31/538 ; A61K31/454 ; A61K31/4709 ; A61K31/547 ; C07D413/12 ; C07D413/14 ; C07D401/12 ; C07D417/12 ; A61P9/12

Abstract:
The present invention relates to a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, being useful as a renin inhibitor. [wherein R1a is halogen, etc.; R1m is H, etc.; G1 is —N(R1b)—, etc.; G2 is —CO—, etc.; G3 is —C(R1c)(R1d)—, etc.; G4 is oxygen, etc.; R1b is optionally substituted C1-6 alkyl, etc.; R1c and R1d are independently the same or different, H, etc.; R3 is H, optionally substituted C1-6 alkyl, etc.; R3a, R3b, R3c and R3d are independently the same or different, and a group: -A-B (said A is single bond, etc., and said B is H, etc.), etc.; and n is 1, etc.]
Public/Granted literature
- US20110190278A1 BICYCLIC HETEROCYCLIC DERIVATIVE Public/Granted day:2011-08-04
Information query
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