A system and methods of subtraction of a shaped component of a noise reduction spectrum from a combined signal are disclosed. In an embodiment, a method includes identifying a selected frequency component using a corresponding frequency component of a noise sample spectrum. A noise set is comprised of the noise sample spectrum. The method further includes forming a shaped component of a noise reduction spectrum using a processor and a memory based on a combined signal spectrum and the selected frequency component. The method also includes subtracting the shaped component of the noise reduction spectrum from the combined signal spectrum.