A data processing method for a non-volatile memory device is provided. The non-volatile memory device includes a controller and a NAND flash memory. First, a target command and a corresponding target address are serially transmitted from the controller to the NAND flash memory. Then, the NAND flash memory calculates a first value according to the target address. Moreover, a cyclic redundancy check code corresponding to the target address is transmitted from the controller transmits to the NAND flash memory. Next, the NAND flash memory determines whether a transmission error has occurred by performing a cyclic redundancy check according to the first value and the cyclic redundancy check code. When the transmission error has occurred, a status register is set to inform the controller to re-transmit the target command and the corresponding target address.