A motorcycle has a rear wheel brake lever provided on a handlebar and a rear wheel brake provided on a rear wheel. A rear wheel brake cable is connected to the rear wheel brake lever and the rear wheel brake. A main frame extends toward the rear part from the front part of the motorcycle. The main frame is disposed at a center in a vehicle width direction and extends toward the rear part of the vehicle body on the upper side of an engine unit. The rear wheel brake cable is laid toward the rear part from the front part of the vehicle body along the main frame. The transmitting loss of brake operation is thereby reduced and swing of the rear wheel brake cable is prevented.