Invention Grant
US08394582B2 Identification of fetal DNA and fetal cell markers in maternal plasma or serum
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鉴定母体血浆或血清中的胎儿DNA和胎儿细胞标志物
- Patent Title: Identification of fetal DNA and fetal cell markers in maternal plasma or serum
- Patent Title (中): 鉴定母体血浆或血清中的胎儿DNA和胎儿细胞标志物
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Application No.: US10547721Application Date: 2004-03-05
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Publication No.: US08394582B2Publication Date: 2013-03-12
- Inventor: Ralph Michael Bohmer
- Applicant: Ralph Michael Bohmer
- Applicant Address: AU
- Assignee: Genetic Technologies, Inc
- Current Assignee: Genetic Technologies, Inc
- Current Assignee Address: AU
- Agency: Sheridan Ross P.C.
- International Application: PCT/AU2004/000287 WO 20040305
- International Announcement: WO2004/078999 WO 20040916
- Main IPC: G01N33/53
- IPC: G01N33/53 ; C12N5/00 ; C12N5/02
Abstract:
The present invention relates to the identification of fetal specific nucleic acids and fetal cell markers in maternal plasma or serum. In particular, the present invention relates to methods which rely on the analysis of polymorphic alleles of a population to determine an allele which is possessed by the fetus but absent from the mother. Fetal specific alleles identified using the methods of the invention can be used to quantify fetal DNA from maternal plasma or serum. In addition, antigens encoded by alleles identified using the methods of the invention can be targeted in methods of isolating or detecting fetal cells.
Public/Granted literature
- US20070134658A1 Identification of fetal dna and fetal cell markers in maternal plasma or serum Public/Granted day:2007-06-14
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