Invention Grant
US08394593B2 Use of an IL-12 receptor splice variant and molecular assay to quantify expression thereof
有权
使用IL-12受体剪接变体和分子测定来定量其表达
- Patent Title: Use of an IL-12 receptor splice variant and molecular assay to quantify expression thereof
- Patent Title (中): 使用IL-12受体剪接变体和分子测定来定量其表达
-
Application No.: US13022224Application Date: 2011-02-07
-
Publication No.: US08394593B2Publication Date: 2013-03-12
- Inventor: Richard T. Robinson , Andrea M. Cooper
- Applicant: Richard T. Robinson , Andrea M. Cooper
- Applicant Address: US NY Saranac Lake
- Assignee: Trudeau Institute
- Current Assignee: Trudeau Institute
- Current Assignee Address: US NY Saranac Lake
- Agency: Medlen & Carroll, LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/04
Abstract:
The present invention describes compositions for both diagnostic and therapeutic applications. In one embodiment, the present invention contemplates a vaccine formulation comprising an antigen and IL12Rβ1 isoform 2. In some embodiments, this invention relates to a method of quantifying the ratio of IL12Rβ1 transcript and a splice variant thereof in a sample, including but not limited to at the cDNA level. In other embodiments, this invention relates to a method of augmenting an immune response by administering, inhibiting and/or inducing IL12Rβ1 isoform 2.
Public/Granted literature
- US20110256158A1 NOVEL USE OF AN IL-12 RECEPTOR SPLICE VARIANT AND MOLECULAR ASSAY TO QUANTIFY EXPRESSION THEREOF Public/Granted day:2011-10-20
Information query
