Invention Grant
- Patent Title: Methods and compositions for risk stratification
- Patent Title (中): 风险分层的方法和组成
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Application No.: US12778847Application Date: 2010-05-12
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Publication No.: US08394599B2Publication Date: 2013-03-12
- Inventor: Omar D. Perez , Garry P. Nolan , Jonathan M. Irish
- Applicant: Omar D. Perez , Garry P. Nolan , Jonathan M. Irish
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Bozicevic, Field & Francis LLP
- Agent Elizabeth A. Alcamo
- Main IPC: G01N33/574
- IPC: G01N33/574 ; C12N5/00
Abstract:
The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of potentiators of cellular activation allows for characterization of such pathways and cell populations.
Public/Granted literature
- US20100221750A1 Methods and Compositions for Risk Stratification Public/Granted day:2010-09-02
Information query
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