Invention Grant
- Patent Title: Two-component genome flavivirus and uses thereof
-
Application No.: US12151491Application Date: 2008-05-07
-
Publication No.: US08394620B2Publication Date: 2013-03-12
- Inventor: Ilya V. Frolov , Alexandr V. Shustov
- Applicant: Ilya V. Frolov , Alexandr V. Shustov
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of The University of Texas System
- Current Assignee: The Board of Regents of The University of Texas System
- Current Assignee Address: US TX Austin
- Main IPC: C12N7/00
- IPC: C12N7/00 ; A61K39/12
Abstract:
The present invention discloses a two-component genome flavivirus and a method for propagating such virus. Since the genetic material of this flavivirus is distributed between two genomes, the flavivirus is deficient in replication, incapable of causing disease but capable of inducing an immune response. Nevertheless, the design of the replication deficient flavivirus discussed herein allows propagation of these flaviviruses at industrial level.
Public/Granted literature
- US20090324623A1 Two-component genome flavivirus and uses thereof Public/Granted day:2009-12-31
Information query
