Invention Grant
US08394810B2 Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof
有权
作为蛋白质脱乙酰酶抑制剂的反酰胺化合物及其使用方法
- Patent Title: Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof
- Patent Title (中): 作为蛋白质脱乙酰酶抑制剂的反酰胺化合物及其使用方法
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Application No.: US13010974Application Date: 2011-01-21
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Publication No.: US08394810B2Publication Date: 2013-03-12
- Inventor: John H. van Duzer , Ralph Mazitschek , Walter Ogier , James E. Bradner , Guoxiang Huang , Dejian Xie , Nan Yu
- Applicant: John H. van Duzer , Ralph Mazitschek , Walter Ogier , James E. Bradner , Guoxiang Huang , Dejian Xie , Nan Yu
- Applicant Address: US MA Boston
- Assignee: Acetylon Pharmaceuticals
- Current Assignee: Acetylon Pharmaceuticals
- Current Assignee Address: US MA Boston
- Agency: Lathrop & Gage LLP
- Agent Brian C. Trinque; Giulio A. DeConti
- Main IPC: A61K31/505
- IPC: A61K31/505
Abstract:
The present invention relates to novel “reverse amide” compounds comprising a zinc chelator group, and the use of such compounds in the inhibition of HDAC6 and in the treatment of various diseases, disorders or conditions related to HDAC6.
Public/Granted literature
- US20110300134A1 REVERSE AMIDE COMPOUNDS AS PROTEIN DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF Public/Granted day:2011-12-08
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