Invention Grant
- Patent Title: Activated blood coagulation factor inhibitor
- Patent Title (中): 活化凝血因子抑制剂
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Application No.: US13181596Application Date: 2011-07-13
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Publication No.: US08394821B2Publication Date: 2013-03-12
- Inventor: Makoto Ono
- Applicant: Makoto Ono
- Applicant Address: JP Tokyo
- Assignee: Daiichi Sankyo Company, Limited
- Current Assignee: Daiichi Sankyo Company, Limited
- Current Assignee Address: JP Tokyo
- Agency: Locke Lord LLP
- Priority: JP2009-004904 20090113
- Main IPC: C07D215/38
- IPC: C07D215/38 ; A61K31/04

Abstract:
An object of the present invention is to provide a novel salt form of a compound that exhibits an inhibitory effect on activated blood coagulation factor X, and is useful as a preventive and/or therapeutic drug for thrombotic diseases, and crystals thereof. The present invention provides N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide tartrate and crystals thereof, as a novel salt form of N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide and crystals thereof.
Public/Granted literature
- US20110312991A1 ACTIVATED BLOOD COAGULATION FACTOR INHIBITOR Public/Granted day:2011-12-22
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