Invention Grant
US08394831B2 Carbonylamino-derivatives as novel inhibitors of histone deacetylase
有权
羰基氨基衍生物作为组蛋白脱乙酰酶的新型抑制剂
- Patent Title: Carbonylamino-derivatives as novel inhibitors of histone deacetylase
- Patent Title (中): 羰基氨基衍生物作为组蛋白脱乙酰酶的新型抑制剂
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Application No.: US13280207Application Date: 2011-10-24
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Publication No.: US08394831B2Publication Date: 2013-03-12
- Inventor: Kristof Van Emelen , Marc Gustaaf Celine Verdonck , Sven Franciscus Anna Van Brandt , Leo Jacobus Jozef Backx
- Applicant: Kristof Van Emelen , Marc Gustaaf Celine Verdonck , Sven Franciscus Anna Van Brandt , Leo Jacobus Jozef Backx
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica, N.V.
- Current Assignee: Janssen Pharmaceutica, N.V.
- Current Assignee Address: BE Beerse
- Agency: Woodcock Washburn LLP
- Priority: EP014074 20021210
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/4439
Abstract:
This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, R5, L, Q, X, Y and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20120041001A1 CARBONYLAMINO-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE Public/Granted day:2012-02-16
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