Invention Grant
- Patent Title: Pyrrolidines as NK3 receptor antagonists
- Patent Title (中): 吡咯烷作为NK3受体拮抗剂
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Application No.: US12856691Application Date: 2010-08-16
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Publication No.: US08394834B2Publication Date: 2013-03-12
- Inventor: Philippe Jablonski , Henner Knust , Matthias Nettekoven , Angelique Patiny-Adam , Hasane Ratni , Claus Riemer
- Applicant: Philippe Jablonski , Henner Knust , Matthias Nettekoven , Angelique Patiny-Adam , Hasane Ratni , Claus Riemer
- Applicant Address: US NJ Nutley
- Assignee: Hoffman-La Roche Inc.
- Current Assignee: Hoffman-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP09168630 20090825
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; C07D401/14
Abstract:
The present invention relates to a compounds of formula I wherein R1, R2, Ar1, Ar2, R′, R″, m, n, and o are defined in the specification or to a pharmaceutically active salt, racemic mixture, enantiomer, optical isomer or to tautomeric form thereof. The present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).
Public/Granted literature
- US20110053948A1 PYRROLIDINES AS NK3 RECEPTOR ANTAGONISTS Public/Granted day:2011-03-03
Information query
IPC分类:
