Invention Grant
US08394990B2 Phenylurea inhibitors of the enzyme SOAT-1 and pharmaceutical/cosmetic compositions comprised thereof
失效
酶SOAT-1的苯基脲抑制剂和由其组成的药物/化妆品组合物
- Patent Title: Phenylurea inhibitors of the enzyme SOAT-1 and pharmaceutical/cosmetic compositions comprised thereof
- Patent Title (中): 酶SOAT-1的苯基脲抑制剂和由其组成的药物/化妆品组合物
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Application No.: US12717984Application Date: 2010-03-05
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Publication No.: US08394990B2Publication Date: 2013-03-12
- Inventor: Thibaud Portal
- Applicant: Thibaud Portal
- Applicant Address: FR Biot
- Assignee: Galderma Research & Development
- Current Assignee: Galderma Research & Development
- Current Assignee Address: FR Biot
- Agency: SNR Denton US LLP
- Priority: FR0757392 20070906
- Main IPC: C07C273/00
- IPC: C07C273/00 ; A61K31/445
Abstract:
Phenylurea compounds of formula (I): are inhibitors of the enzyme SOAT-1. Cosmetic and pharmaceutical compositions containing them are useful for treating various disorders, such as acne, or have cosmetic applications. An exemplary species is 1-[1-(biphenyl-2-ylamino)cyclopentylmethyl]-3-(2,6-diisopropylpheny)urea.
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