The invention relates to a device for setting a fastener element (55) having an inner pin (56) slidable relative to an outer body (57) and comprising a locking arrangement (32, 33; 38, 39) comprising a bolt (19) provided for acting on the inner pin (56) and secured in a retracted position against axial displacement into an advanced position after relatively spacing a handle body (52) and an actuating organ (8, 46). When the actuating organ (8, 46) is actuated by a displacement opposite the retraction direction, an unlatching organ (40, 41) acts on the locking arrangement (32, 33; 38, 39) and releases the bolt (19) for displacing into the advanced position. Very simple handling of the manually actuated device is thus ensured.